Although agriculture supplies the ever-growing need for food and other products of human, but at the same time it’s one of the main causes of greenhouse gas emission, genetic diversity loss, chemical pollution as well as soil degradation. Concerns about the sustainability of traditional agriculture has drawn the attention to the alternative farming systems such as organic planting and transgenic products that are compatible with the environment. A review of the resources and various statistical analyzes have shown that although organic farming has less efficiency than traditional agriculture but it provides nutritionally valuable or even higher nutrients without pesticide residues. On the other hand, in the case of pest or disease damage occurrence in the organic product, a large amount of saprophytic fungi may develop which cause toxic and carcinogenic mycotoxins emergence. Therefore, in order to produce enough food at an affordable price for a growing population in the world that is expected to reach 7 billion by 2030, and also to provide livelihoods for farmers as well as to reduce the environmental impact of agricultural practices, the combination of old and new methods in agriculture, and the use of modern science and technology especially transgenic products can solve many of the food and environmental problems in the world. Transgenic plants resistant to pests and diseases can be used in integrative and organic farming to reduce the consumption of pesticides. The cultivation of transgenic plants is in line with organic farming goals including the reduction of pesticide usage. Hence, the term "organogenetic" is defined as the transplant of organic products and transgenic products.